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sodium 2-methyl-3-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,1-dioxo-1lambda6,2-benzothiazin-4-olate

Dangerous Goods

CAS number:71125-39-8    molecular formula:C14H12N3NaO4S2

overview

compound introduction

Meloxicam 钠盐水合物已被证明可消除胸腺素诱导的大鼠肝脏中细胞因子和NGF的增加,并抑制肿瘤生长。Meloxicam 可能能够拮抗恶病质。Meloxicam 是一种非甾体抗炎药(NSAID),相对于Cox-1(cyclooxygenase-1)抑制作用,其对Cox-2(cyclooxygenase-2)的抑制作用具有300倍的选择性。 Meloxicam sodium salt hydrate has been shown to abolish thymulin-induced increases of cytokines and NGF in the liver of rats and displays tumor growth suppression. Meloxicam may be capable of antagonizing cachexia|in vitro|. Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) that shows 300-fold selectivity for Cox-2 (cyclooxygenase-2) inhibition versus Cox-1(cyclooxygenase-1) inhibition.

Specs

Chinese alias-
English alias-
CAS number71125-39-8molecular formulaC14H12N3NaO4S2
molecular weight373.4Exact mass-
PSA139logp-

numbering system

CAS71125-39-8
ChEMBL IDCHEMBL1256873
PubChem CID4051
DSSTox Substance IDDTXSID601017452
PubChem Reference Collection SID500799848

physicochemical properties

复杂性634
溶解度>56 [ug/mL] (pH 7.4时结果的平均值)
Exact Mass373.01669250
形式电荷0
重原子计数24
Molecular Weight373.4
Monoisotopic Mass373.01669250
可旋转键计数2
氢键供体计数1
氢键受体计数7
共价键单元计数2
同位素原子计数0
拓扑极性表面积139 Ų
Collision Cross Section174.5 Ų [M+H]+ [CCS 类型:TW;方法:用聚丙氨酸和药物标准品校准]
定义键立体中心计数0
定义原子立体中心计数0
未定义键立体中心计数0
未定义原子手性中心计数0

Safety information

WGK Germany:
3

Production methods and uses

purpose
工业应用参考:
工业分类参考:医药制造业。 应用场景参考:在环境监测、水资源分析、矿产检测、农残筛查和大气污染研究等方向具备潜在应用空间 。 作用参考:可用于改善产品性能、稳定性或使用体验,在配方优化和质量提升中具备辅助价值 。 选型提示:不同品牌和不同标准体系下的技术参数可能存在差异,应用前应优先核对规格、检测方法和质量要求 。

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MSDS

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