Ganetespib(STA-9090)是含三唑酮的Hsp90抑制剂,在OSA 8细胞中IC50为4 nM。A unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM for OSA 8 cells Ganetespib(STA-9090) is a unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM in OSA 8 cells. A unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM for OSA 8 cells
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Ganetespib (STA-9090)
Dangerous GoodsCAS number:888216-25-9 molecular formula:C20H20N4O3
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | EX-A250 | 3-(2,4-Dihydroxy-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-1H-1,2,4-triazol-5(4H)-one | AS-35117 | FT-0700397 | 3-(2,4-dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one | HMS3654K12 | BCP22669 | CHEBI:177770 | GANE | ||
| CAS number | 888216-25-9 | molecular formula | C20H20N4O3 |
| molecular weight | 364.4 g/mol | Exact mass | ≥98% |
| PSA | 90.100 Ų | logp | 3.1 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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