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Bortezomib Pinanediol Ester

Dangerous Goods

CAS number：205393-22-2    molecular formula：C29H39BN4O4

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overview

compound introduction

（1R）-（1S，2S，3R，5S）-P二醇-N-（N-吡嗪基苯基丙氨酰基）-1-氨基-3-甲基丁烷-1-硼酸酯是制备硼替佐米和二肽基硼酸酯蛋白酶体抑制剂的中间体。 (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methylbutane-1-boronate is an intermediate in the preparation of Bortezomib and a dipeptidyl boronate proteasome inhibitor.

Specs

Chinese alias-
English alias(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate
CAS number205393-22-2molecular formulaC29H39BN4O4
molecular weight518.46 g/molExact mass≥97%
PSA102.000 Ųlogp-

numbering system

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physicochemical properties

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Safety information

Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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