Tianeptine

Dangerous Goods

CAS number：72797-41-2 molecular formula：C21H25ClN2O4S

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Information Tianeptine Tianeptine (S-1574, JNJ-39823277, TPI-1062) is an antidepressant agent that act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors. Targets 5-HT ; μ-opioid receptor (for human μ-opioid receptor) ; 383 nM(Ki) In vitro Tianeptine modulates glutamatergic transmission. It restores stress-induced reduction of dendritic arborization in hippocampal neurons and reverses stress-induced inhibition of long-term potentiation at excitatory synapses in the hippocampus and prefrontal cortex. Tianeptine is a serotonin reuptake enhancer and has an antidepressant efficacy. In vivo In preclinical studies, tianeptine has beneficial effects in a number of behavioral models related to depression, anxiety and other stress-related disorders.

Specs

Chinese alias	-
English alias	7-((3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid \| 7-[[(11R)-3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl]amino]heptanoic acid \| HY-90003 \| 7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-diox
CAS number	72797-41-2	molecular formula	C21H25ClN2O4S
molecular weight	436.95 g/mol	Exact mass	≥98%
PSA	95.100 Å²	logp	1.222

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08

Signal word：

Warning

Hazard Statement：

H373: 通过长时间或反复暴露对器官造成损害 H361: 怀疑破坏生育力或未出生的孩子 H362: 可能对母乳喂养的孩子造成伤害

Statement of Preventive Measures：

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P263: 避免在怀孕期间/哺乳期间接触。 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。 P319: 如果你感到不适，请寻求医疗帮助。