All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry

Apixaban

Dangerous Goods

CAS number：503612-47-3    molecular formula：C25H25N5O4

overview
Specs
numbering system
physicochemical properties
Safety information
Production methods and uses
Related
MSDS
related products

overview

compound introduction

Apixaban是一种高度选择性，可逆的凝血因子 Xa 抑制剂，抑制人和兔凝血因子 Xa 的 Ki 值分别为 0.08 nM 和 0.17 nM。Apixaban 正在开发用于预防和治疗各种血栓栓塞疾病。 Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. Apixaban is in development for the prevention and treatment of various thromboembolic diseases.

Specs

Chinese alias阿哌沙班
English aliasFT-0686944 | SCHEMBL118023 | 1H-PYRAZOLO(3,4-C)PYRIDINE-3-CARBOXAMIDE, 4,5,6,7-TETRAHYDRO-1-( 4-METHOXYPHENYL)-7-OXO-6-(4-(2-OXO-1-PIPERIDINYL)PHENYL)- | 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3-
CAS number503612-47-3molecular formulaC25H25N5O4
molecular weight459.51 g/molExact mass-
PSA111.000 Ųlogp2.2

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：
GHS08
Signal word：
Danger
Hazard Statement：
H373: 通过长时间或反复暴露对器官造成损害 H372: 通过长时间或反复暴露对器官造成损害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P319: 如果你感到不适，请寻求医疗帮助。

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
503612-47-3 | Apixaban.pdf