CAS number：1229236-86-5 molecular formula：C23H25ClFN7O
LY2784544是一种有效的JAK2抑制剂，IC50为3 nM，作用于JAK2V617F有效，比作用于JAK1和JAK3选择性高8和20倍。Phase 2。A selective inhibitor of JAK2 mutant V617F. LY2784544 is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2. A selective inhibitor of JAK2 mutant V617F.
| Chinese alias | - | ||
| English alias | C23H25ClFN7O | 3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine | AKOS037643413 | D10365 | D78334 | Gandotinib;3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpho | ||
| CAS number | 1229236-86-5 | molecular formula | C23H25ClFN7O |
| molecular weight | 469.95 g/mol | Exact mass | - |
| PSA | 83.400 Ų | logp | 3.8 |
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