CAS number：717907-75-0 molecular formula：C21H20F3N7O3S
PF-562271是一种有效的，ATP竞争性的，可逆的FAK抑制剂，IC50为1.5 nM，作用于Pyk2比作用于FAK选择性低10倍左右，比作用于其他蛋白激酶（除了一些CDKs）选择性高100倍以上。 PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs
| Chinese alias | - | ||
| English alias | CHEBI:91370 | EX-A1385 | Q27163236 | HMS3265N12 | HMS3651D06 | Kinome_3857 | TS-01949 | 717907-75-0 (free base) | HMS3265M12 | MFCD16038299 | CCG-265006 | GTPL9381 | N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl | ||
| CAS number | 717907-75-0 | molecular formula | C21H20F3N7O3S |
| molecular weight | 507.49 g/mol | Exact mass | - |
| PSA | 138.000 Ų | logp | 2 |
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