CAS number：957054-30-7 molecular formula：C23H27N7O3S2
GDC-0941是PI3Kα/δ抑制剂，IC50为3 nM，比对p110β和p110γ的抑制性强11倍和25倍。A potent inhibitor the PI 3-kinase family Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Phase 2. A potent inhibitor the PI 3-kinase family
| Chinese alias | - | ||
| English alias | s7808 | TXCWBWKVIZGWEQ-UHFFFAOYSA-N | HMS3244H10 | HMS3265J06 | Pictilisib [USAN:INN] | s1065 | Pictilisib (USAN) | Q27088388 | 4-[2-(1H-indazol-4-yl)-6-[(4-methylsulfonyl-1-piperazinyl)methyl]-4-thieno[3,2-d]pyrimidinyl]morpholine | DTXSID40241930 | EC-0 | ||
| CAS number | 957054-30-7 | molecular formula | C23H27N7O3S2 |
| molecular weight | 513.64 g/mol | Exact mass | - |
| PSA | 144.000 Ų | logp | 1.6 |
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