compound introduction
PF-04929113 (SNX-5422)是一种有效的，选择性的HSP90抑制剂，Kd为41 nM，且诱导Her-2降解，IC50为37 nM。Phase 1/2。 PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.
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PF-04929113 (SNX-5422)
CAS number：908115-27-5 molecular formula：C25H30F3N5O4
overview
Specs
| Chinese alias | 甘氨酸反式-4-[[2-(氨基羰基)-5-[4,5,6,7-四氢-6,6-二甲基-4-氧代-3-(三氟甲基)-1H-吲唑-1-基]苯基]氨基]环己酯 | ||
| English alias | (1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl glycinate | BBL027742 | ETHYL CYANOACETATE [HSDB] | EX-A2343 | PF-04929113 (SNX-5422) | Acetal resin | Glycine Trans-4-((2-(aminoc | ||
| CAS number | 908115-27-5 | molecular formula | C25H30F3N5O4 |
| molecular weight | 521.54 g/mol | Exact mass | ≥98% |
| PSA | 142.000 Ų | logp | 3.5 |
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