CAS number：956958-53-5 molecular formula：C21H16N6O2S2
XL147是一种选择性的，可逆的I型PI3K抑制剂，对PI3Kα/δ/γ有抑制作用，IC50分别为39 nM/36 nM/23 nM，对PI3Kβ作用效果稍弱。 XL147 is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM, less potent to PI3Kβ. An ATP-competetive class I PI3K inhibitor.
| Chinese alias | - | ||
| English alias | AKOS022131419 | MFCD16621245 | BCP01861 | N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide | N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methyl-benzenesulfonamide | XL147-II | AC-23168 | BRD-K95901403-001-01-1 | ||
| CAS number | 956958-53-5 | molecular formula | C21H16N6O2S2 |
| molecular weight | 448.52 g/mol | Exact mass | - |
| PSA | 146.000 Ų | logp | 4.200 |
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