CAS number：722544-51-6 molecular formula：C26H30FN7O3
AZD1152-HQPA是AZD-1152的活性代谢物，AZD1152-HQPA (Barasertib)是Aurora B 高选择性抑制剂，IC50为0.37 nM，比对Aurora A的抑制性高100倍。A highly selective ARK-2 inhibitor AZD1152-HQPA is the active metabolite of AZD-1152, AZD1152-HQPA (Barasertib) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM, ~100 fold more selective for Aurora B over Aurora A. A highly selective ARK-2 inhibitor
| Chinese alias | - | ||
| English alias | DTXSID60222584 | INH-34 | 2-[5-[[7-[3-[ethyl(2-Hydroxyethyl)amino]propoxy]quinazolin-4-Yl]amino]-1h-Pyrazol-3-Yl]-N-(3-Fluorophenyl)ethanamide | Barasertib_HQPA | barasertib-hQPA | AM81250 | EN300-25886121 | 29P8LWS24N | BCP9000359 | HMS3265M01 | SCHEMBL1 | ||
| CAS number | 722544-51-6 | molecular formula | C26H30FN7O3 |
| molecular weight | 507.56 g/mol | Exact mass | - |
| PSA | 128.000 Ų | logp | 3.000 |
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