GW788388是一种有效的,选择性的ALK5抑制剂,IC50为18 nM,也抑制其他TGF-βI型和II型受体激酶活性,但不抑制BMP II型受体 GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibits TGF-β type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor
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GW788388
CAS number:452342-67-5 molecular formula:C25H23N5O2
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| Chinese alias | - | ||
| English alias | FT-0700309 | HMS3656N21 | UNII-N14114957J | Q27284368 | N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}benzamide | A6195 | AC-31390 | BCP04559 | BCP9000754 | Benzamide, 4-(4-(3-(2-pyridinyl)-1H-pyrazol-4-yl)-2-pyridinyl)-N-(tetrahydro-2 | ||
| CAS number | 452342-67-5 | molecular formula | C25H23N5O2 |
| molecular weight | 425.48 g/mol | Exact mass | ≥98% |
| PSA | 92.800 Ų | logp | 2.700 |
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