Palomid 529 (P529)抑制mTORC1和mTORC2复合体,降低pAktS473, pGSK3βS9和pS6磷酸化,但是对pMAPK和pAktT308没有作用效果 Palomid 529 (P529) inhibits both the mTORC1 and mTORC2 complexes, reduces phosphorylation of pAktS473, pGSK3βS9, and pS6 but no effect observed on pMAPK or pAktT308. A novel PI3K/Akt/mTOR inhibitor with a GI50 of
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Palomid 529 (P529)
Dangerous GoodsCAS number:914913-88-5 molecular formula:C24H22O6
overview
compound introduction
Specs
| Chinese alias | 帕罗米德 529 (P529) | ||
| English alias | 8-(1-hydroxyethyl)-2-methoxy-3-((4-methoxyphenyl)methoxy)-6h-dibenzo(b,d)pyran-6-one | (z)-ocimene | Oroxylin A, >=98% (HPLC) | SCHEMBL290034 | SG00529 | SW219676-1 | Palomid 529 (P529) | 6-methoxy-4'-methylapigenin | RES-529 | s2238 | 8-(1-Hydroxyethyl)- | ||
| CAS number | 914913-88-5 | molecular formula | C24H22O6 |
| molecular weight | 406.43 g/mol | Exact mass | ≥98% |
| PSA | 74.200 Ų | logp | 4 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS06
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒
Statement of Preventive Measures:
P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽:立即寻求紧急医疗救助。
WGK Germany:
3
RTECS:
HP8756500
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