compound introduction
AZD8055是ATP竞争性mTOR抑制剂，IC50为0.8 nM，比对PI3K和ATM/DNA-PK的抑制性强超过1000倍。 AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM with excellent selectivity (～1,000-fold) against PI3K isoforms and ATM/DNA-PK.
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AZD8055
Dangerous GoodsCAS number：1009298-09-2 molecular formula：C25H31N5O4
overview
Specs
| Chinese alias | - | ||
| English alias | (5-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol | GTPL7714 | KVLFRAWTRWDEDF-IRXDYDNUSA-N | SMR004701277 | HY-W010629 | 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy benzenemetha | ||
| CAS number | 1009298-09-2 | molecular formula | C25H31N5O4 |
| molecular weight | 465.56 g/mol | Exact mass | - |
| PSA | 93.100 Ų | logp | 2.6 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
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MSDS
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