WZ8040是突变选择型不可逆EGFRT790M抑制剂,对ERBB2磷酸化(T798I)无抑制性。A potent inhibitor of EGFR T790M WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I). A potent inhibitor of EGFR T790M
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WZ8040
CAS number:1214265-57-2 molecular formula:C24H25ClN6OS
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| Chinese alias | - | ||
| English alias | AKOS027276489 | EX-A4023 | SW219395-1 | W-108455 | FT-0728045 | WZ8040 | WZ-8040 | F82898 | AC-32056 | CCG-269557 | SCHEMBL93523 | SMR004703030 | N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide | DTXSID4065 | ||
| CAS number | 1214265-57-2 | molecular formula | C24H25ClN6OS |
| molecular weight | 481.02 g/mol | Exact mass | ≥98% |
| PSA | 98.700 Ų | logp | 4.800 |
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