compound introduction
MK-0731 是一种选择的、非竞争性变构纺锤体驱动蛋白 (KSP) 抑制剂，IC50为 2.2 nM，pKa为 7.6。MK-0731 对其他驱动蛋白的选择性 >20,000 倍。MK-0731 诱导有丝分裂停滞并诱导肿瘤细胞凋亡。MK-0731 具有显着的抗肿瘤功效。
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MK-0731
CAS number：845256-65-7 molecular formula：
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 845256-65-7 | molecular formula | |
| molecular weight | 459.500 g/mol | Exact mass | ≥99% |
| PSA | 47.000 Ų | logp | 2.800 |
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