compound introduction
(R)-(−)-蜂蜜曲菌素是一种由a.ochraceus Wilhelm产生的二氢异香豆素化合物。它具有多种生物活性，包括抗菌、抗疟疾、抗真菌和抗癌作用。(R)-(−)-蜂蜜曲菌素抑制IC50值大于200μM的人类乳腺癌症（MCF-7和MDA-MB-468）和黑色素瘤（SK-MEL-28和Malme-3M）细胞系的增殖。 (R)-(−)-Mellein is an antibiotic isolated from culture fluids of this Aspergillus. (R)-(−)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(−)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and Malme-3M) cell lines with IC50 values greater than 200 μM.
