CAS number：726169-73-9 molecular formula：C23H20N6O
Mocetinostat (MGCD0103)是一种有效的HDAC抑制剂，对HDAC1抑制作用最强，IC50为0.15 μM，比作用于HDAC2， 3，和11选择性高2到10倍，对HDAC4， 5， 6， 7，和8没有抑制活性。Phase 2。A potent inhibitor of HDAC1, HDAC2, HDAC3, and HDAC11. Mocetinostat (MGCD0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Phase 2. A potent inhibitor of HDAC1, HDAC2, HDAC3, and HDAC11.
| Chinese alias | - | ||
| English alias | MFCD10565970 | MGCD0103 - Mocetinostat | NCGC00263182-11 | UNII-A6GWB8T96J | DTXSID80222945 | HMS3426I07 | STK387500 | SCHEMBL157027 | AKOS015916602 | MG 0103 | BRD-K16485616-001-04-8 | FT-0627651 | HRNLUBSXIHFDHP-UHFFFAOYSA-N | MOCETINOSTAT [INN] | N-(2- | ||
| CAS number | 726169-73-9 | molecular formula | C23H20N6O |
| molecular weight | 396.44 g/mol | Exact mass | - |
| PSA | 106.000 Ų | logp | 2.8 |
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