All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry

Monascin

CAS number:21516-68-7    molecular formula:C21H26O5

overview

compound introduction

红曲色素是可从红曲米中提取得到的一种氮杂类色素,有口服活性,具有抗肿瘤和抗炎活性。红曲色素还能抑制NOR 的激活。红曲色素是一种 Nrf2 激活剂和 PPARγ 激动剂。 应用: 红曲霉素已被用于治疗4T1乳腺癌细胞和测试其对癌细胞失巢凋亡和生长抑制的效果。 Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist. Application: Monascin has been used to treat 4T1 breast cancer cells and to test its effects on tumor cells anoikis and growth prevention.

Specs

Chinese alias红曲 | 单子叶黄素 | (3,3a,9a)-3-己酰基-9a-甲基-6-(-丙烯基)3a,4,8,9a-四氢-3氢-呋喃并[3,2-g]异染色质-2,9-二酮 | (3,3a,9a)-3a,4,8,9a-四氢-9a-甲基-3-(1-氧代己基)-6-(1E)-1-丙烯基-2氢-呋喃[3,2-g][2]苯并吡喃-2,9(3氢)-二酮
English aliasMonascoflavin | (3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione | (3S,3aR,9aR)-3a,4,8,9a-Tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
CAS number21516-68-7molecular formulaC21H26O5
molecular weight358.43 g/molExact mass≥98%
PSA69.700 Ųlogp3.200

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

No safety information yet

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
21516-68-7 | (3S) -3a α, 4,8,9a tetrahydro 9a β methyl-3- (1-oxohexyl) -6- [ (E) -1-propenyl] -2H-furo [3,2-G] [2] benzopyran-2,9- (3H) -dione | Monascin