All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry

N-Glycolylneuraminic Acid(Neu5Gc)

Dangerous Goods

CAS number:1113-83-3    molecular formula:C11H19NO10

overview

compound introduction

N-羟乙酰神经氨酸(Neu5Gc)是最常见的唾液酸,它是由于N-乙酰神经氨酸(Neu5Ac)的5-N-乙酰结构单元中甲基的羟基化形成。它主要存在于海胆和海星中,也广泛分布于精子细胞和卵母细胞的糖蛋白和神经节苷脂中。Neu5Gc属于Sia家族。 产品应用 N-羟乙酰神经氨酸已被用于: ①作为微量滴定生物膜(microtiter biofilm )方法中的糖用于改善生物膜形成; ②作为标准品用于测定量蚕神经系统中的唾液酸,并用于发现不同发育阶段唾液酸的变化; ③作为高效液相色谱(HPLC)分析中的标准品用于以1,2-二氨基-4,5-亚甲基二氧苯(DMB)为荧光化合物检测唾液酸(Sia)分子。 N-Glycolylneuraminic acid (Neu5Gc) is the most common sialic acid formed as a result of the hydroxylation of the methyl group of the 5-N-acetyl moiety of N-acetylneuraminic acid (Neu5Ac). It is predominantly found in sea urchins and starfish and is broadly distributed in glycoproteins and gangliosides of sperm cells and oocyte. Neu5Gc belongs to the family of Sia. Product Application N-Glycolylneuraminic acid has been used: ①as a sugar in microtiter biofilm methodologic approach for the enhancement of biofilm formation. ②as a standard for the determination of sialic acids in the nervous system of silkworm and to find the variations of sialic acids among different developmental stages. ③as a standard in the high-performance liquid chromatography (HPLC) analyses to detect the molecular species of sialic acid (Sia) species using 1,2-diamino-4,5-methylenedioxy-benzene (DMB) as a fluorogenic compound.

Specs

Chinese aliasN-羟乙酰神经氨酸
English aliasNeu5Glc | NeuNGl
CAS number1113-83-3molecular formulaC11H19NO10
molecular weight325.27 g/molExact mass≥95%(HPLC)
PSA197.000 Ųlogp-4.100

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

WGK Germany:
3
Personal protective equipment:
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
1113-83-3 | N-Hydroxyacetylneuraminic acid | N-Glycolylneuraminic acid