储存在-20℃。存放在干燥的条件下。该产品最多可存储12个月。 MNS (NSC 170724) 是 β-硝基苯乙烯衍生物，是一种有效的酪氨酸激酶抑制剂和广谱抗血小板药物。MNS 完全抑制 U46619、ADP、花生四烯酸、胶原和凝血酶诱导的血小板聚集，IC50 值分别为 2.1、4.1、5.8、7.0 和 12.7 μM。MNS 抑制 Src、Syk 和 FAK，IC50 分别为 27.3、2.8 和 97.6 μM。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. product description： A cell-permeable nitrostyrene compound that acts as a selective inhibitor of Syk kinase activity (IC50 = 2.5 µM). It inhibits Src only at much higher concentrations (IC50 = 29.3 µM) and exhibits little effect against Fak and JAK2. Shown to potently inhibit platelet aggregation induced by various stimulators, including U46619, ADP, arachidonic acid, collagen, thrombin, ionophore A23187, and PDBu (IC50 ranges from 2.1 to 25.9 µM). Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic ac
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MDBN
Dangerous GoodsCAS number：1485-00-3 molecular formula：C9H7NO4
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 5-[(E)-2-nitroethenyl]-2H-1,3-benzodioxole | AI3-02050 | NCGC00261282-01 | NSC 105303 | Syk Inhibitor III | 5-(2-Nitro-vinyl)-benzo[1,3]dioxole | EN300-83338 | SBB007833 | BDBM50155928 | Ethene, 1-(3,4-methylendioxyphenyl)-2-nitro- | NCGC00186015-06 | 3,4 | ||
| CAS number | 1485-00-3 | molecular formula | C9H7NO4 |
| molecular weight | 193.16 g/mol | Exact mass | - |
| PSA | 64.300 Ų | logp | 2.400 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06 , GHS07
Signal word：
Danger
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H301: 吞咽会中毒
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水
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MSDS
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