脂肪族和芳香族羟基和氨基保护试剂组 · 2，2，2-三氯乙基氯甲酸酯被用作气相色谱/质谱法测定血浆、尿液和头发样品中大量苯丙胺相关药物和麻黄碱的衍生试剂。在合成 6-去甲-9，10-二氢麦角酸甲酯时，将其用作起始试剂。 · 它在右美沙芬的 N-去甲基化过程中用作试剂。 · 它被用作脂族和芳族羟基和氨基的保护试剂。 2,2,2-三氯氯甲酸乙酯（TrocCl）是一种用途广泛的试剂，用于有机合成中的选择性酰化和脱烷基化。它可用于区位、化学和立体选择性合成 2,2,2-Trichloroethyl chloroformate (TrocCl) serves as a versatile reagent used for selective acylation and dealkylation in organic synthesis. It is used in regio, chemo, and stereoselective synthesis. 2,2,2-Trichloroethyl chloroformate was used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples； It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester； It was used as reagent during N-demethylation of dextromethorphan； It was used as protecting reagent for aliphatic and aromatic hydroxyl and amino groups； Protecting reagent for aliphatic and aromatic hydroxyl and amino groups.
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2,2,2-Trichloroethyl chloroformate
Dangerous GoodsCAS number：17341-93-4 molecular formula：C3H2Cl4O2
overview
compound introduction
Specs
| Chinese alias | 氯甲酸三氯乙酯 | 三氯乙氧基甲酰氯 | ||
| English alias | 2,2-Trichloroethoxycarbonyl chloride | .BETA.,.BETA.,.BETA.-TRICHLOROETHOXYCARBONYL CHLORIDE | AKOS015917631 | Trichloroethyl chloroformate | 2,2,2-trichloroethylchloroformate | 2,2,2-trichloroethyl-chloroformate | Carbonochloridic acid,2,2-trichloroethyl | ||
| CAS number | 17341-93-4 | molecular formula | C3H2Cl4O2 |
| molecular weight | 211.86 g/mol | Exact mass | ≥99% |
| PSA | 26.300 Ų | logp | 3.000 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS06 , GHS05 , GHS07
Signal word：
Danger
Hazard Statement：
H331: 吸入会中毒 H314: 造成严重的皮肤灼伤和眼睛损伤 H302: 吞食有害 H330: 吸入致命
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良，请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P301+P330+P331: 如误吞咽：漱口。不要诱
WGK Germany：
3
Personal protective equipment：
Faceshields,full-face respirator (US),Gloves,Goggles,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter
UN Number：
3277
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
17341-93-4 | 2,2,2-Trichloroethyl chloroformate.pdf
