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Malonitrile

Dangerous Goods

CAS number:109-77-3    molecular formula:C3H2N2

overview

compound introduction

能溶于醇、醚,水和苯,微溶于氯仿和乙酸。有毒,半数致死量(小鼠,腹腔)12.9mg/kg。有刺激性。有机合成原料。医药方面,用于合成维生素B1、氨蝶呤、氨苯蝶啶等一系列重要药物。染料方面、农药方面及其他方面都有重要的用途。也可用作金的萃取剂。中国现主要用于生产氨苯蝶啶、苄嘧黄隆、1,4,5,8-萘四甲酸、嘧啶系列产品。 丙二腈,一种弱氰基碳酸,是一种反应性超高的多功能化合物。这种结晶脂肪族腈可用作合成杂环化合物和聚合物的合成砌块 应用 丙二腈可用于:碱促进的[1,6]-萘啶水上合成;γ--酮酰胺的合成;特殊杂环药物支架(包括吡啶、1,4-二氢吡啶、苯并吡喃[2,3-b]吡啶和二氢-1,4-二噻吩骨架)的制备 Malononitrile, a weak cyanocarbon acid, is a versatile compound with exceptional reactivity, widely used in condensation reactions. Malononitrile may be used in the base-promoted on-water synthesis of [1,6]-naphthyridines; synthesis of γ-ketoamides;preparation of heterocyclic privileged medicinal scaffolds involving pyridine, 1,4-dihydropyridine, chromeno[2,3-b]pyridine and dihydro-1,4-dithiepine frameworks. Malonitrile, a weak cyanocarbonic acid, is a highly reactive multifunctional compound. This crystalline aliphatic nitrile can be used as a synthetic block for the synthesis of heterocyclic compounds and polymers

Specs

Chinese alias氰基乙腈 | 二氰甲烷 | 亚甲基二腈 | 二氰基甲烷
English aliasMALONONITRILE [MI] | EINECS 203-703-2 | Malononitril | DTXCID701907 | 1,1-dicyanomethane | Dicyanmethane | FT-0689819 | Malononitrile, >=99% | EN300-19714 | J-002327 | Malonic dinitrile | Nitrile kyseliny malonove | Nitrile kyseliny malonove [Czech] | Nit
CAS number109-77-3molecular formulaC3H2N2
molecular weight66.06 g/molExact mass升华级
PSA47.600 Ųlogp-0.500

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS06 , GHS09
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒 H311: 皮肤接触有毒 H331: 吸入会中毒 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P
WGK Germany:
3
Personal protective equipment:
dust mask type N95 (US),Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges
RTECS:
OO3150000
UN Number:
2647
General hazardous chemicals:
一般危化品
Packing Group:
II

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
109-77-3 | malononitrile | dicyanomethane | methylene cyanide