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Nosiheptide

CAS number:56377-79-8    molecular formula:C51H43N13O12S6

overview

compound introduction

Nosiheptide是一种由多种放线菌|链霉菌|产生的双环硫肽抗生素。与其他双环硫肽(例如硫链丝菌素)不同,第二个大环环通过相对脆弱的内酯和硫代内酯桥连接到核心环肽上。Nosiheptide具有广谱抗菌活性,并且最近证明与万古霉素相比,在医院和社区获得的MRSA中,抗生素延长了后效。 Product Describtion: Nosiheptide is a bicyclic thiopeptide antibiotic produced by several species of|actinomycetes|, notably|Streptomyces|. Unlike other bicyclic thiopeptides such as thiostrepton, the second macrocyclic ring is linked by relatively fragile lactone and thiolactone bridges to the core cylic peptide. Nosiheptide has broad spectrum antibacterial activity, and has recently demonstrated a prolonged post-antibiotic effect in both nosocomial and community-acquired MRSA compared with vancomycin. Product Application: Nosiheptide is an antibacterial item used in feedstock and feed additives for chickens.

Specs

Chinese alias-
English aliasSR-01000945025-1 | Nosiheptide | SR-01000945025 | Nosiheptide, Antibiotic for Culture Media Use Only | MFCD30718117 | Multhiomycin | SCHEMBL945554 | EX-A819 | W-105523 | C12053 | Nosiheptide (USAN/INN) | 4-Thiazolecarboxamide,N-[1-(aminocarbonyl)ethenyl]-
CAS number56377-79-8molecular formulaC51H43N13O12S6
molecular weight1222.36 g/molExact mass≥96%
PSA552.000 Ųlogp4.100

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