Raltegravir (MK-0518)是一种有效的整合酶链转移抑制剂,作用于WT和S217Q原型泡沫病毒(PFV)整合酶,IC50分别为90 nM和40 nM。A potent integrase strand transfer inhibitor for (PFV) IN. Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectively. A potent integrase strand transfer inhibitor for (PFV) IN.
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Raltegravir (MK-0518)
CAS number:518048-05-0 molecular formula:C20H21FN6O5
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| Chinese alias | 雷特格韦 | ||
| English alias | GTPL11571 | SCHEMBL996804 | 3-oxo-estra-4,9,11-triene-17b-ol | FT-0649660 | hydropyrimidine-4-carboxamide | 4-chloro-7-nitro-2,1,3-benzooxadiazole | Raltegravir- Bio-X | HYDROXYZINE PAMOATE [VANDF] | J05AX08 | NCGC00274066-05 | AKOS015902444 | N-(2-(4-(4- | ||
| CAS number | 518048-05-0 | molecular formula | C20H21FN6O5 |
| molecular weight | 444.42 g/mol | Exact mass | - |
| PSA | 150.000 Ų | logp | 1.100 |
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