It is a nitrosylated N-methyl aniline that is described to form adducts with DNA. N-Nitroso-N-methylaniline is useful for studying enzymatic denitrosation processes. N-demethylation of N-Nitroso-N-methylaniline catalysed by cytochrome P450 is described to proceed throμgh an electrophilic benzenediazonium ion which is demonstrated to form triazene DNA adducts at the N6-position of adenine residuesA compounds used to study enzymatic denitrosation It is a nitrosylated N-methyl aniline that is described to form adducts with DNA. N-Nitroso-N-methylaniline is useful for studying enzymatic denitrosation processes. N-demethylation of N-Nitroso-N-methylaniline catalysed by cytochrome P450 is described to proceed through an electrophilic benzenediazonium ion which is demonstrated to form triazene DNA adducts at the N6-position of adenine residues A compounds used to study enzymatic denitrosation
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N-Nitroso-N-methylaniline
Dangerous GoodsCAS number：614-00-6 molecular formula：C7H8N2O
overview
compound introduction
Specs
| Chinese alias | N-亚硝基甲胺苯 | ||
| English alias | 1-Methyl-2-oxo-1-phenylhydrazine # | 9SM68I29WQ | DTXCID801053 | HSDB 5072 | N-Nitrosomethylphenylamine | LS-13273 | N-Methyl-N-nitrosoaniline | N-methyl-N-nitroso-aniline | SCHEMBL301282 | F16699 | AI3-01373 | Methylnitrosoaniline | N-Methyl-N-phenylnitr | ||
| CAS number | 614-00-6 | molecular formula | C7H8N2O |
| molecular weight | 136.15 g/mol | Exact mass | ≥98% |
| PSA | 32.700 Ų | logp | 1.700 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS06 , GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H319: 引起严重眼睛刺激 H301: 吞咽会中毒 H311: 皮肤接触有毒 H351: 怀疑引起遗传缺陷
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P361+P364: 立即脱掉所有沾染的衣服，清洗后方可重新使用。 P
RTECS：
BY5775000
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
614-00-6 | N-Nitrosomethylphenylamine (NMPA).pdf
