Ethoxycarbonyl isothiocyanate

Dangerous Goods

CAS number：16182-04-0 molecular formula：SCNCOOCH2CH3

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Ethoxycarbonyl isothiocyanate reacts with 2-amino-tetrahydrobenzo[b]thiophene derivatives to yield tetrahydrobenzo[b]thiophen-2-thiourea derivatives.用于以甲锡烷基芳烃合成硫脲的通用试剂，从 2-氨基-2-噁唑啉制备 1,3,5-三嗪-2-酮-4-硫酮,以及用氨基脱氧糖合成 N-酰基硫脲。 Ethoxycarbonyl isothiocyanate reacts with 2-amino-tetrahydrobenzo[b]thiophene derivatives to yield tetrahydrobenzo[b]thiophen-2-thiourea derivatives. Versatile reagent used to synthesize thiocarbamides from stannylarenes, 1,3,5-triazin-2-one-4-thiones from 2-amino-2-oxazolines,and N-acylthioureas fromaminodeoxy sugars. application： Ethoxycarbonyl isothiocyanate has been used in the synthesis of:pyrazolo[1,5-a][1,3,5]triazine derivatives, potential inhibitors of protein kinase CK2；fused thiophene derivatives, having antibacterial and antifungal activities；4-thiouracil derivatives；thiocarbamides from stannylarenes；1,3,5-triazin-2-one-4-thiones from 2-amino-2-oxazolines；N-acylthioureas from aminodeoxy sugars. Ethoxycarbonyl isothiocyanate, is used as a building block in the synthesis of various heterocycles. It is also used for the synthesis of 1,2,4-oxadiazolidine-3,5-dione. It is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Specs

Chinese alias	异硫氰酸乙氧羰酯 \| 异硫氰酰甲酸乙酯
English alias	alpha-D-Glucopyranose, 4-o-alpha-D-glucopyranosyl- \| ETHYL CARBONISOTHIOCYANATIDATE \| ethyl N-(sulfanylidenemethylidene)carbamate \| ethoxy carbonyl isothiocyanate \| AB00381 \| ethoxycarbonylisothiocyanat \| ethoxycarbonyl-isothiocyanat \| AMY10862 \| Ethyl is
CAS number	16182-04-0	molecular formula	SCNCOOCH2CH3
molecular weight	131.15 g/mol	Exact mass	≥98%
PSA	70.800 Å²	logp	2.300

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS06 , GHS08 , GHS07 , GHS02

Signal word：

Danger

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H331: 吸入会中毒 H302: 吞食有害 H317: 可能引起皮肤过敏反应 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难 H312: 皮肤接触有害 H226: 易燃液体和蒸气 H332: 吸入有害

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P370+P378: 火灾时：使用干砂、干粉或抗醇泡沫灭火。 P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/

WGK Germany：

Personal protective equipment：

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter