用于合成带有保护基团的吡咯脯氨酸的结构单元。 该氨基醛的 α-亚甲基化反应可通过一种快速而有效的途径进行，采用最近报道的包括甲醛以及吡咯烷丙酸或二肽 (L-Pro-β-Ala) 的催化作用在内的方案。 还可用于吡咯烷三组分合成反应（包括 1,3-偶极环加成反应）。 N -Boc-2-氨基乙醛是一种有机构件。与 Horner-Wadsworth-Emmons (HWE) 试剂反应，得到 γ-氨基丁酸 (GABA) 衍生的 α-酮酰胺/酯单元。 N-Boc-2-aminoacetaldehyde is an organic building block. It reacts with Horner-Wadsworth-Emmons (HWE) reagent to afford γ-aminobutyric acid (GABA)-derived α-keto amide/ester units. N-Boc-2-aminoacetaldehyde may be employed in the following: . As a starting reagent in the total synthesis of (+)-negamycin. . Synthesis of (E)-ethyl 4-((tert-butoxycarbonyl)amino)but-2-enoate. . Synthesis of 2,2′-bipyridine. N-Boc-2-aminoacetaldehyde is used in the synthesis of carbohydrates as well as studies relating to inhibitors of cathepsin K.
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N-Boc-2-aminoacetaldehyde
Dangerous GoodsCAS number：89711-08-0 molecular formula：HCOCH2NHCO2C(CH3)3
overview
compound introduction
Specs
| Chinese alias | N-(2-氧代乙基)氨基甲酸叔丁酯 | N-叔丁氧羰基-2-氨基乙醛 | ||
| English alias | N-(2-Oxoethyl)-carbamic acid Tert-Butyl ester | Carbamic acid, (2-oxoethyl)-, 1,1-dimethylethyl ester | FT-0649527 | tert-butyl (2-oxoethyl)carbamate | tert-butyl N-(2-oxoethyl)carbamate;N-Boc-2-aminoacetaldehyde | (2-Oxo-ethyl)-carbamic acid tert-butyl e | ||
| CAS number | 89711-08-0 | molecular formula | HCOCH2NHCO2C(CH3)3 |
| molecular weight | 159.18 g/mol | Exact mass | ≥90% |
| PSA | 55.400 Ų | logp | 0.500 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
Production methods and uses
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MSDS
Found 1 shareMSDS
89711-08-0 | N-Boc-2-aminoacetaldehyde.pdf
