compound introduction
乙酰哌普嗪是一种有效的多巴胺受体拮抗剂和吩噻嗪类抗精神病剂。乙酰哌普嗪能够直接结合 PAX3::FOXO1 融合蛋白并抑制其转录活性。乙酰哌普嗪也具有抗肿瘤作用，对 PANC-1 细胞的 IC50 为 7.627 μM。乙酰哌普嗪可用于精神分裂症和胰腺癌等肿瘤的研究。 Piperacetazine is an active dopamine receptor antagonist and phenothiazine antipsychotic. Piperacetazine can directly bind to the PAX3::FOXO1 fusion protein and inhibit its transcriptional activity. Piperacetazine also exhibits antitumor activity with an IC50 of 7.627 μM against PANC-1 cells. Piperacetazine can be used for the research of diseases such as schizophrenia and pancreatic cancer and other tumors.
