栎精-3,5,7,3',4'-五甲醚是一种分离自小花山奈中的多甲氧基黄酮。在分化早期,它可以调控转录因子,促进 3T3-L1 前脂肪细胞形成脂肪。 生物活性: 栎精-3,5,7,3',4'-五甲醚是一种 Ca2+ 通道 (Ca2+ channel) 抑制剂。3,5,7,3’,4’-Pentamethoxyflavone 可以保护 DNA 免受氧化损伤。栎精-3,5,7,3',4'-五甲醚可通过钙动员相关机制引起人类海绵体松弛。栎精-3,5,7,3',4'-五甲醚在中年雄性大鼠中可以促进血管 eNOS 和胱硫氨酸-γ-裂解酶 CSE 蛋白的表达,并调节血管功能。栎精-3,5,7,3',4'-五甲醚可用于糖尿病和心血管疾病的研究。 Quercetin 3,5,7,3,4-pentamethyl ether is a natural product. It can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation. Biological activity 3,5,7,3’,4’-Pentamethoxyflavone is a Ca2+ channel inhibitor. 3,5,7,3’,4’-Pentamethoxyflavone can protect DNA from oxidative damage. 3,5,7,3’,4’-Pentamethoxyflavone can induce relaxation of the human corpus cavernosum through calcium mobilization-related mechanisms. 3,5,7,3’,4’-Pentamethoxyflavone can promote the expression of eNOS and cystathionine gamma lyase CSE proteins in middle-aged male rats and regulate vascular function. 3,5,7,3’,4’-Pentamethoxyflavone can be used in research related to diabetes and cardiovascular diseases.
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Quercetin-3,5,7,3',4'-pentaMethylether
CAS number:1247-97-8 molecular formula:C20H20O7
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Specs
| Chinese alias | 2-(3,4-二甲氧基苯基)-3,5,7-三甲氧基-4H-苯并吡喃-4-酮 | 槲皮素3,5,7,3',4'-五甲基醚 | ||
| English alias | 2-(3,4-Dimethoxyphenyl)-3,5,7-trimethoxy-4H-chromen-4-one | 3,5,7,3′,4′-Pentamethoxyflavone | ||
| CAS number | 1247-97-8 | molecular formula | C20H20O7 |
| molecular weight | 372.37 g/mol | Exact mass | - |
| PSA | 72.500 Ų | logp | 3.200 |
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