Tricetin is mainly found in natural plants such as Ginkgo biloba L., Carica papaya L. and Murraya exotica L. Tricetin activates the Nrf2/HO-1 pathway to protect cells from oxidative stress. Tricetin possessed the protective effect on dopamine neurons of C. elegans . Tricetin has cytostatic properties and anti-metastatic activity of various solid tumors. Pretreatment with Tricetin (20, 40, and 80 μM; for 4 hours) significantly improves 6-OHDA (200 μM)-induced SH-SY5Y cells viability and suppresses mitochondria-mediated apoptosis. Tricetin (80 μM; for 1, 2 and 4 h) markedly decreased the expressions of p-JNK and p-p38. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay Cell Line: SH-SY5Y cells Concentration: 20, 40, and 80 μM Incubation Time: Pretreatment for 4 h followed by 6-OHDA (200 μM) for 24 h Result: Significantly increased 6-OHDA-induced SH-SY5Y cells viability. Western Blot Analysis Cell Line: SH-SY5Y cells Concentration: 80 μM Incubation Time: 1, 2 and 4 h Result: Markedly decreased the expressions of p-JNK and p-p38.
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Tricetin
Dangerous GoodsCAS number：520-31-0 molecular formula：C15H10O7
overview
compound introduction
Specs
| Chinese alias | 三粒小麦黄酮 | 五羟基黄酮 | 三黄素 | ||
| English alias | SPBio_000722 | AKOS024287743 | MYF | Spectrum4_001678 | SpecPlus_000826 | 5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one | C10192 | KBio2_004639 | BP-10199 | AR-683/41530196 | BSPBio_003253 | Tricetin | MS-24353 | NCGC00095682-02 | KBioGR_ | ||
| CAS number | 520-31-0 | molecular formula | C15H10O7 |
| molecular weight | 302.24 g/mol | Exact mass | - |
| PSA | 127.000 Ų | logp | 1.000 |
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
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