CAS number：870653-45-5 molecular formula：C21H18O5
Kv1.3钾离子通道的选择性抑制剂。 PAP-1 is selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity for Kv1.3 over Kv1.5, and 33-125-fold selectivity over other Kv1 family channels. In treatment of multiple sclerosis
| Chinese alias | Kv1.3抑制剂 | 4-(4-苯氧基丁氧基)-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮 | ||
| English alias | PAP-1 | HY-10015 | AKOS015920200 | SPS-4251 | 5-(4-Phenoxybutoxy)psoralen;4-(4-Phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | 4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one | 4-[4-(phenoxy)butoxy]furo[3,2-g]chromen-7-one | AC-1703 | Cis-11-tetradecen -1-ol | Q | ||
| CAS number | 870653-45-5 | molecular formula | C21H18O5 |
| molecular weight | 350.36 g/mol | Exact mass | - |
| PSA | 57.900 Ų | logp | 4.7 |
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