compound introduction
PP1是一种有效的Src选择性抑制剂，作用于Lck/Fyn时，IC50为5 nM/6 nM。 Application: PP1 has been used as: an inhibitor of sarcoma (Src) family kinases (SFK) like hematopoietic cell kinase (hck) and fyn a selective Src tyrosine kinase inhibitor in hippocampal neuronal cultures to test its effect on neurite growth a Src-kinase blocker to test its effect on brimonidine (BMD)-induced phosphorylation in extracellular signal-activated kinases(ERK1/2) PP1 is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM. A selective and potent Src family tyrosine kinase inhibitor.
