W-7 has been reported to be a calmodulin (CaM) antagonist that inhibits Ca2+/calmodulin-regulated enzyme activities. Injection of murine tails with W-7 has demonstrated this agents ability to decrease tolerance to antinociceptive effects, therefore, CaM and its dependent pathways have demonstrated the capacity to play a role in antinociceptive agent tolerance processes. This cell permeable compound has been found to inhibit proliferation of hamster ovary K1 cells. W-7 has also been noted to bind troponin C in the presence of Ca2+ and inhibit striated muscle contractions.A calmodulin (CaM) antagonist and antiproliferative agent. W-7 has been reported to be a calmodulin (CaM) antagonist that inhibits Ca2+/calmodulin-regulated enzyme activities. Injection of murine tails with W-7 has demonstrated this agents ability to decrease tolerance to antinociceptive effects, therefore, CaM and its dependent pathways have demonstrated the capacity to play a role in antinociceptive agent tolerance processes. This cell permeable compound has been found to inhibit proliferation of hamster ovary K1 cells. W-7 has also been noted to bind troponin C in the presence of Ca2+ and inhibit striated muscle contractions. A calmodulin (CaM) antagonist and antiproliferative agent. Application N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride has been used to study its effect of on coated pit staining.
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N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride
Dangerous GoodsCAS number：61714-27-0 molecular formula：C16H21ClN2O2S·HCl
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| Chinese alias | - | ||
| English alias | ALEXIDINE [MART.] | N-(6-aminohexyl)-5-chloronaphthalene-1-sulfonamide;hydrochloride | NCGC00178278-01 | W-7, Hydrochloride - CAS 61714-27-0 | SMR000326845 | C16092 | AKOS024457749 | N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULPHONAMIDE HYDROCHLORIDE | SPEC | ||
| CAS number | 61714-27-0 | molecular formula | C16H21ClN2O2S·HCl |
| molecular weight | 377.33 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 80.600 Ų | logp | - |
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Safety information
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
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