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Antipain, Dihydrochloride

Dangerous Goods

CAS number:37682-72-7    molecular formula:C27H44N10O6.2HCl

overview

compound introduction

抗痛素二盐酸盐是由放线菌产生的可逆蛋白酶抑制剂。抗痛药抑制组织蛋白酶A,B和D以及木瓜蛋白酶,胰蛋白酶和类胰蛋白酶的丝氨酸蛋白酶。止痛药通过在抑制剂的醛基和活性蛋白酶之间形成半缩醛加合物起作用。在1至100μM的浓度范围内有效。 Antipain, Dihydrochloride is a reversible protease inhibitor produced by actinomycetes. Antipain inhibits cathepsin A, B, and D as well as papain, trypsin and trypsin-like serine proteases. Antipain acts by forming a hemiacetal adduct between the aldehyde group of the inhibitor and the active proteinase. Effective at concentrations range from 1 to 100 μM.

Specs

Chinese alias-
English alias[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal . 2HCl | Antipain, Dihydrochloride | Antipain dihydrochloride from microbial source, protease inhibitor | (9S,12S)-1-amino-16-benzyl-6-formyl-12-(3-guanidinopropyl)-1-imino-9-isopropyl-8,11,14-trioxo
CAS number37682-72-7molecular formulaC27H44N10O6.2HCl
molecular weight677.62 g/molExact mass≥95%
PSA283.000 Ųlogp-

numbering system

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physicochemical properties

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Safety information

WGK Germany:
3
RTECS:
YV9350800

Production methods and uses

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MSDS

Found 1 shareMSDS
37682-72-7 | 68305 MannheimDeutschland.pdf