抗坏血酸钠是潜在的抗氧化剂，是维生素C（L-抗坏血酸）的衍生物。作为食品添加剂，广泛应用。此外，SA还增强硫酸博来霉素、R020-1724（环状核苷酸磷酸二酯酶抑制剂）、前列腺素E1和丁酸钠等物质的生长阻滞活性，这一活性对培养的神经母细胞瘤细胞有作用。升高的SA水平会诱发大鼠二期膀胱癌。[1] L-抗坏血酸钠与胶原蛋白生成抑制剂联合用于治疗皮肤疤痕和瘢痕疙瘩。 应用： 用于制备植物提取物;用于分离叶绿体的还原剂。 抗坏血酸钠用于： · 在细胞培养基中，产生过H2O2； · 作为还原剂，还原可渗透细胞人工电子供体（N，N，N，′N′-四甲基对苯二胺（TMPD））； · 研究其对源自正常人体皮肤和真皮脂肪成纤维细胞培养物中胶原蛋白和弹性纤维产量的影响。 Sodium ascorbate is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid).[1][2] It is widely used as a food additive.[1] In addition, SA enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture.[3] Elevated levels of SA induces two-stage urinary bladder carcinogenesis in rats.[1] sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids. Application： Sodium ascorbate has been used: · to produce H2O2 in cell culture media; · as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD); · to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat.
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Sodium ascorbate
Dangerous GoodsCAS number：134-03-2 molecular formula：C6H7NaO6
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compound introduction
Specs
| Chinese alias | 维生素C钠盐 | L-抗坏血酸钠 | ||
| English alias | L-Ascorbic acid, monosodium salt | sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate | Vitamin C Sodium Salt | (+)-Sodium L-ascorbate | SODIUM ASCORBATE | 2,3-Didehydro-L-theo-hexono-1,4-lactone sodium enolate | SODIUM ASCORBATE (US | ||
| CAS number | 134-03-2 | molecular formula | C6H7NaO6 |
| molecular weight | 198.11 g/mol | Exact mass | 用于细胞培养 |
| PSA | 110.000 Ų | logp | - |
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physicochemical properties
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Safety information
WGK Germany：
1
Personal protective equipment：
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS：
CI7671000
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MSDS
Found 1 shareMSDS
134-03-2 | (+)-Sodium L-ascorbate.pdf
