Lobeline hydrochloride

Dangerous Goods

CAS number：134-63-4 molecular formula：C22H28ClNO2

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physicochemical properties

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MSDS

overview

compound introduction

盐酸洛贝林是烟碱样受体激动剂, 作为有效的神经元烟碱受体α3β2和α4β2拮抗剂。 Lobeline hydrochloride is an alkaloid that acts on nicotinic cholinergic receptors but is less potent than nicotine. It is also a VMAT2 ligand and an antagonist of μ-opioid receptors. Solubility ≥37.5 mg/mL in EtOH with ultrasonic; ≥37.8 mg/mL in H2O with gentle warming and ultrasonic; ≥74.8 mg/mL in DMSO

Specs

Chinese alias	-
English alias	LOBELINE HYDROCHLORIDE \| 134-63-4 \| 2-(6-(2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride \| 63990-84-1 \| Zoolobelin \| (-)-Lobeline hydrochloride \| 2-(6-(beta-Hydroxyphenethyl)-1-methyl-2-piperidyl)acetophenone hydrochloride
CAS number	134-63-4	molecular formula	C22H28ClNO2
molecular weight	373.93 g/mol	Exact mass	10mM in DMSO
PSA	40.500 Å²	logp	-

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physicochemical properties

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Safety information

pictogram：

GHS06

Signal word：

Danger

Hazard Statement：

H301: 吞咽会中毒 H331: 吸入会中毒

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P330: 漱口 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P316: