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Cytochalasin B from Drechslera dematioidea

Dangerous Goods

CAS number:14930-96-2    molecular formula:C29H37NO5

overview

compound introduction

源于Drechslera dematioidea的细胞松弛素B已被用于: 阻断胞质分裂,获得双核细胞 作为特异性葡萄糖转运体抑制剂 抑制I、III类GLUT对葡萄糖的转运,测定HCMV感染细胞和模拟感染细胞的50%抑制浓度(IC50) 细胞松弛素B用于抑制成纤维细胞中的糖转运,减少兔中性粒细胞中的细胞骨架肌动蛋白和肌球蛋白,并刺激B淋巴细胞。 Cytochalasin B from Drechslera dematioidea has been used: to block cytokinesis, to obtain binucleated cells as a specific glucose transporter inhibitor to inhibit glucose transport by class I and III GLUTs to determine the 50% inhibitory concentration (IC50) in HCMV-infected and mock-infected cells Cytochalasin B is used to inhibit sugar transport in fibroblasts , decrease cytoskeletal actin and myosin in rabbit neutrophils, and to stimulate B lymphocytes.

Specs

Chinese alias-
English aliasC19954 | IDI1_034070 | MLS002703001 | SCHEMBL9046718 | 2H-Oxacyclotetradec(2,3-d)isoindole-2,18(5H)-dione, 16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-, (E,E)-(5S,9R,12aS,13S,15S,15aS,16S,18aS)- | BDBM
CAS number14930-96-2molecular formulaC29H37NO5
molecular weight479.61 g/molExact mass-
PSA95.900 Ųlogp3.400

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS06 , GHS08
Signal word:
Danger
Hazard Statement:
H300: 吞咽致命 H310: 与皮肤接触致命 H330: 吸入致命 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P301+P310: 如误吞咽:立即呼叫急救中心/医生。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良,请佩戴呼吸防护装置。 P302+P350: 如果皮肤接触:用大量肥皂和水轻轻清洗。
WGK Germany:
3
Personal protective equipment:
Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges
RTECS:
RO0205000
UN Number:
1544

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
14930-96-2 | Cytochalasin B Formulation Solution | Cytochalasin B, from Drechslera dematioidea