Cytochalasin J

Dangerous Goods

CAS number：53760-20-6 molecular formula：C28H37NO4

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

细胞松弛素J用于肌动蛋白聚合研究。细胞松弛素是有效的霉菌毒素，其结合到肌动蛋白丝的带刺的末端，从而抑制了亚基的缔合和解离。用作细胞学研究的工具。这些真菌毒素的化学结构与其特征相关，该化学结构的特征是高度取代的氢化异吲哚环，该环与大环稠合。细胞松弛素J是细胞松弛素H的脱乙酰基类似物，尽管具有较低的效力，抗菌，抗真菌，杀线虫和抗肿瘤活性，但它们具有相似的活性。 Cytochalasin J is used in actin polymerization studies. Cytochalasins are potent mycotoxins which bind to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. These fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. Cytochalasin J is the deacetyl analogue of cytochalasin H and exhibits similar, though less potent, antibacterial, antifungal, nematocidal and antitumor activities. Application： Cytochalasin J is a cell-permeable fungal toxin used in actin polymerization studies and cytological research

Specs

Chinese alias	-
English alias	(1R,2R,3Z,5R,7S,9Z,11R,12S,14S,15R,16S)-16-benzyl-2,5,12-trihydroxy-5,7,14-trimethyl-13-methylidene-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-18-one \| Cytochalasin j
CAS number	53760-20-6	molecular formula	C28H37NO4
molecular weight	451.6 g/mol	Exact mass	≥95%
PSA	-	logp	-

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS06 , GHS08

Signal word：

Danger

Hazard Statement：

H351: 怀疑引起遗传缺陷 H300: 吞咽致命 H310: 与皮肤接触致命 H330: 吸入致命

Statement of Preventive Measures：

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良，请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持

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