CAS number：208255-80-5 molecular formula：C23H26F2N2O4
DAPT (GSI-IX)是一种新型γ-分泌酶抑制剂，抑制HEK 293细胞中全部Aβ产量， IC50为20 nM。A potent and specific inhibitor of γ-secretase. DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells. A potent and specific inhibitor of γ-secretase.
| Chinese alias | N-[N-(3,5-二氟苯乙酰)-L-丙氨酰]-S-苯甘氨酸叔丁酯 | (3,5-二氟苯乙酰基)-Ala-Phg-OtBu | (3,5-二氟苯乙酰基)-L-丙氨酰基-L-2-苯基甘氨酸叔丁酯 | ||
| English alias | Glycine, N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)- | MRF-0000012 | (S)-tert-butyl 2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate | HY-13027G | KBio2_001007 | GSI IX | DWJXYEABWRJFSP-XOBRGWD | ||
| CAS number | 208255-80-5 | molecular formula | C23H26F2N2O4 |
| molecular weight | 432.46 g/mol | Exact mass | - |
| PSA | 84.500 Ų | logp | 3.700 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
