Estrogen receptor modulator 1 (compound 18) 是一种口服活性选择性雌激素受体 (estrogen receptor) 调节剂 (SERM),pIC50 为 0.46。Estrogen receptor modulator 1 诱导 Tamoxifen 耐药、激素非依赖性异种移植瘤的消退。
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2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol
Dangerous GoodsCAS number:63676-22-2 molecular formula:C14H10O2S
overview
compound introduction
Specs
| Chinese alias | 2-(4-羟苯基)苯并[b]噻吩-6-醇 | 雌激素受体调节剂1 | ||
| English alias | 6-HYDROXY-2-(4-HYDROXYPHENYL)-BENZO(B)THIOPHENE | FT-0709145 | DB08773 | DTXSID70332204 | H1628 | AC-8398 | MFCD16619490 | 2-(4-Hydroxyphenyl)benzo[b]thiophen-6-ol | EC 691-840-2 | UNII-8ZK5PJ1CM3 | HY-110201 | 2-(4-hydroxyphenyl)-1-benzothiophen-6-ol | A | ||
| CAS number | 63676-22-2 | molecular formula | C14H10O2S |
| molecular weight | 242.29 g/mol | Exact mass | ≥98% |
| PSA | 68.700 Ų | logp | 3.900 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H413: 可能对水生生物造成长期的有害影响
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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