(-)-Indolactam V is a PKC activator (Kis: 3.36 nM, 1.03 μM for η-CRD2 , γ-CRD2). (-)-Indolactam V also has the Kds are 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), 213 nM (γ-C1B). It has antitumor activity.
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(-)-Indolactam V
CAS number:90365-57-4 molecular formula:C17H23N3O2
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compound introduction
Specs
| Chinese alias | (2S,5S)-1,2,4,5,6,8-六氢-5-(羟甲基)-1-甲基-2-(1-甲基乙基)-3H-吡咯并[4,3,2-gh]-1,4-苯并重氮-3-酮 | (-)-吲哚美坦V | 吲哚内酰胺 V | (2S,5S)-5-(羟甲基)-2-异丙基-1-甲基-4,5,6,8-四氢-1H-[1,4]二氮杂环壬烷并[7,6,5-cd]吲哚-3(2H)-酮 | ||
| English alias | HY-12307 | MS-24344 | NCGC00345085-01 | (+-)-IL-V | SCHEMBL1278694 | (-)-IndolactamV | CHRYSOPHANIC ACID [WHO-DD] | INDOLACTAM V, (-) | PDSP1_001380 | Indolactam V | AS-17451 | (10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1. | ||
| CAS number | 90365-57-4 | molecular formula | C17H23N3O2 |
| molecular weight | 301.38 g/mol | Exact mass | - |
| PSA | 68.400 Ų | logp | 2.300 |
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