Pregnenolone is an endogenous neurosteroid that is involved in the steroidogenesis of progesterone, glucocorticoids, mineralocorticoids, androgens, and estrogens, making it a prohormone. It has been observed to inhibit GABA-gated chloride currents by enhancing receptor desensitization. Pregnenolone is an inhibitor of GABA Receptor and an activator of PXR.An prohormone neurosteroid also a precursor to gonadal steroid hormones and the adrenal corticosteroids. Pregnenolone is an endogenous neurosteroid that is involved in the steroidogenesis of progesterone, glucocorticoids, mineralocorticoids, androgens, and estrogens, making it a prohormone. It has been observed to inhibit GABA-gated chloride currents by enhancing receptor desensitization. Pregnenolone is an inhibitor of GABA Receptor and an activator of PXR. An prohormone neurosteroid also a precursor to gonadal steroid hormones and the adrenal corticosteroids.
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Pregnenolone
Dangerous GoodsCAS number：145-13-1 molecular formula：C21H32O2
overview
compound introduction
Specs
| Chinese alias | 孕甾烯醇酮 | ||
| English alias | 3b-Hydroxypregn-5-en-20-one | PREGNENOLONE [WHO-DD] | PREGNENOLONE [INN] | 73R90F7MQ8 | NSC 1616 | Skinostelon | Spectrum5_002057 | 5-Pregnen-3beta-ol-20-one, >=98% | DB02789 | Tox21_112011 | GTPL2376 | HMS3884G16 | Pregnolone | 3beta-Hydroxy-5-pregnene-2 | ||
| CAS number | 145-13-1 | molecular formula | C21H32O2 |
| molecular weight | 316.48 g/mol | Exact mass | - |
| PSA | 37.300 Ų | logp | 4.2 |
numbering system
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physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS07
Signal word：
Warning
Hazard Statement：
H351: 怀疑引起遗传缺陷 H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
145-13-1 | Pregnenolone.pdf
