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Fmoc-D-alpha-(5-bromothienyl)alanine

CAS number:220497-83-6    molecular formula:C22H18BrNO4S

overview

compound introduction

Fmoc-D-α-(5-溴噻吩基)丙氨酸是Fmoc保护的丙氨酸衍生物,可能对蛋白质组学研究和固相肽合成技术有用。丙氨酸是最简单的氨基酸之一-甲基为侧链。当掺入多肽链时,该小侧链赋予高度的灵活性(仅次于甘氨酸)。通常用诸如吡啶之类的碱除去Fmoc基团-这是酸性labile Boc基团的正交脱保护策略。 Fmoc-D-alpha-(5-bromothienyl)alanine is an Fmoc protected alanine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility (second only to glycine) when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

Specs

Chinese alias-
English aliasAKOS037655580 | (2R)-3-(5-bromothiophen-2-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid | Fmoc-D-2-(5-bromothienyl)alanine, AldrichCPR | MFCD01311772 | (alphaR)-5-Bromo-alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-thiophenepropanoic acid
CAS number220497-83-6molecular formulaC22H18BrNO4S
molecular weight472.35 g/molExact mass≥97%
PSA104.000 Ųlogp5.400

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