Product Describtion: 2,2,5,7,8-Pentamethyl-6-chromanol has been reported as an vitamin E model compound. It undergoes oxidation in presence of various alcohols, ranging from methanol to cholesterol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanols.Antioxidant moiety of vitamin E, 2,2,5,7,8-pentamethyl-6-chromanol (PMCol), is reported to have antiandrogen activity in prostate carcinoma cells. Product Application: 2,2,5,7,8-Pentamethyl-6-chromanol is the suitable reagent used for the quantitative analysis of α-tocopherol by plasma-based gas chromatography/tandem mass spectrometry (GC/MS/MS) using a tabletop quadrupole ion trap mass spectrometer. It may be employed as α-tocopherol model compound and on oxidation by t-butyl hydroperoxide in chloroform, in the presence of alcohol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanol. It may be used as internal standard for the determination of α- and γ-tocopherol in the rabbit serum and liver by HPLC.
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2,2,5,7,8-Pentamethyl-6-chromanol
Dangerous GoodsCAS number：950-99-2 molecular formula：C14H20O2
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 3,4-Dihydro-2,2,5,7,8-pentamethyl-2H-1-Benzopyran-6-ol | 2,2,5,7,8-Pentamethyl-6-chromanol # | 2,2,5,7,9-PENTAMETHYL-6-CHROMANOL | NSC-226236 | LEO-124249A | 2,2,5,7,8-pentamethylchroman-6-ol | 2,2,5,7,8-pentamethylchroman-6-ol. | InChI=1/C14H20O2/c1-8-9( | ||
| CAS number | 950-99-2 | molecular formula | C14H20O2 |
| molecular weight | 220.31 g/mol | Exact mass | ≥97% |
| PSA | 29.500 Ų | logp | 3.6 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US)， Eyeshields， Gloves
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
950-99-2 | 2,2,5,7,8-Pentamethyl-6-chromanol.pdf
