TOFA用作可用作:间充质基质细胞(MSC)、人类多功能干细胞中的脂类生化合成抑制剂。小鼠脂肪细胞系中的乙酰-辅酶A羧化酶1抑制剂。一种癌症干细胞(CSC)的脂解抑制剂。 TOFA已被用作 ACC抑制剂,以研究其对 INS-1E细胞中胰岛素分泌的影响。 TOFA has been used as a lipid biosynthesis inhibitor in mesenchymal stromal cells (MSCs), human pluripotent stem cells., an acetyl-CoA carboxylase 1 inhibitor in murine adipocyte cell lines., a lipolysis inhibitor in cancer stem cells (CSCs). TOFA has been used as an ACC inhibitor to study its effect on insulin secretion in INS-1E cells.
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TOFA (5-(tetradecyloxy)-2-furoic acid)
CAS number:54857-86-2 molecular formula:C19H32O4
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Specs
| Chinese alias | - | ||
| English alias | 5-(tetradecyloxy)furan-2-carboxylic acid | HMS3649D14 | 2-Hydroxy-N-(1H-1,2,4-triazol-3-yl)benzamide # | 5-tetradecoxyfuran-2-carboxylic acid | Olumacostat | AKOS015994758 | BCP20578 | AC-35468 | BI12FRY055 | MDL 14514 | UNII-BI12FRY055 | HMS3874J13 | KD- | ||
| CAS number | 54857-86-2 | molecular formula | C19H32O4 |
| molecular weight | 324.46 g/mol | Exact mass | - |
| PSA | 59.700 Ų | logp | 7.800 |
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