compound introduction
Cellocidin是由许多链霉菌属物种产生的小型中性炔烃，最早是由Suzuki及其同事于1958年发现的。Cellocidin具有广泛的抗菌，抗真菌和抗肿瘤特性，因为它能够与半胱氨酸和谷胱甘肽等内源性硫醇反应。Cellocidin在许多使用放线菌粗提物的生物测定中以弱活性存在，因此是化学和生物测定去重复的有用标准。 Cellocidin is a small neutral alkyne produced by a number of Streptomyces species, first discovered by Suzuki and colleagues in 1958. Cellocidin has a broad antibacterial, antifungal and antitumor profile due to its ability to react with endogenous thiols like cysteine and glutathione. Cellocidin occurs as a weak active in many bioassays using actinomycete crude extracts and is thus a useful standard for chemical and bioassay dereplication.
