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Icilin,AG-3-5

Dangerous Goods

CAS number:36945-98-9    molecular formula:C16H13N3O4

overview

compound introduction

General description: Icilin is a synthetic cooling agent and modulates human transient receptor potential cation channel (TRPA1). Icilin inhibits transient receptor potential cation channel subfamily M member 8 (TRPM8) and modulates calcium release. Icilin also suppresses transient receptor potential vanilloid subtype 3 (TRPV3). application: Icilin has been used as cooling agent in anterior ventromedial preoptic area (VMPO) neurons. Biochemical/Physiological Effects: Icilin is a potent agonist at the CMR1 cold- and menthol-sensitive receptor.

Specs

Chinese alias-
English aliasAG 3-5 | AG 3-5; AG3-5; AG-3-5 | EU-0100426 | GTPL2429 | MLS002153471 | 1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidin-2-one | 3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-1,4-dihydropyrimidin-2-one. | Lopac0_000426 | NCGC00025205-01 | NCGC000
CAS number36945-98-9molecular formulaC16H13N3O4
molecular weight311.3 g/molExact mass-
PSA98.400 Ųlogp2.2

numbering system

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physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用

Production methods and uses

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upstream information

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downstream information

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MSDS

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