CAS number：133550-41-1 molecular formula：C20H20N2O3
与HER1 / 2自磷酸化相比，AG 556选择性抑制表皮生长因子受体激酶自磷酸化（IC | 50 | =5μM）。还可以阻止LPS诱导的TNF-α产生。AG 556是EGFR的抑制剂。 AG 556 selectively inhibits epidermal growth factor receptor kinase autophosphorylation (IC|50|= 5μM) over HER1/2 autophosphorylation. Also blocks LPS-induced TNF-α production. AG 556 is an inhibitor of EGFR.
| Chinese alias | - | ||
| English alias | SR-01000597669-2 | Tyrphostin AG556 | 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)- | SCHEMBL18732059 | ag556 | AG-556 | Tocris-0616 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide | Tyrphostin B56 | alpha-Cyano- | ||
| CAS number | 133550-41-1 | molecular formula | C20H20N2O3 |
| molecular weight | 336.39 g/mol | Exact mass | ≥98% |
| PSA | 93.400 Ų | logp | 3.500 |
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