Thiazolyl Blue is a membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT Formazan). Spectrophotometric measurement of MTT Formazan at 540 or 570 nm allows quantitation of cell viability. Thiazolyl Blue is used as a direct indicator of cytotoxicity (such as for screening cancer drμgs) and apoptosis. Thiazolyl Blue is also an electron acceptor used for studying NADP-dependent dehydrogenases.常用于基于MTT检测方法的细胞活力、细胞增殖或细胞毒性检测。因为MTT具有正电荷，它可以穿过细胞膜并被线粒体还原形成紫色甲臜染料。溶解MTT甲臜染料需要使用有机溶剂。脱氢酶的检测，染色法。 Thiazolyl Blue is a membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT Formazan). Spectrophotometric measurement of MTT Formazan at 540 or 570 nm allows quantitation of cell viability. Thiazolyl Blue is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. Thiazolyl Blue is also an electron acceptor used for studying NADP-dependent dehydrogenases. A membrane-permeable dye reduced by mitochondrial enzymes
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3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)
Dangerous GoodsCAS number：298-93-1 molecular formula：C18H16BrN5S
overview
compound introduction
Specs
| Chinese alias | 噻唑蓝(MTT) | 3-(4,5-二甲基-2-噻唑基)-2,5-二苯基溴化四唑 | 2-(4,5-二甲基-2-噻唑基)-3,5-二苯基-2H-四唑氢溴酸盐 | 3-(4,5-二甲基-2-噻唑)-2,5-二苯基溴化四氮唑噻唑蓝 | 3-(4,5-二甲基-2-噻唑基)-2,5-二苯基-2H-四氮唑鎓溴化物 | 噻唑四唑蓝溴化盐 | 噻唑蓝四唑蓝 | ||
| English alias | Thiazolyl blue | 298-93-1 | Thiazolyl blue tetrazolium bromide | MTT | MMT Tetrazolium | Methylthiazoletetrazolium | 2348-71-2 | Thiazolyl Blue Monotetrazolium | 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide | 3-(4,5-Dimethylthiazolyl)-2,5- | ||
| CAS number | 298-93-1 | molecular formula | C18H16BrN5S |
| molecular weight | 414.32 g/mol | Exact mass | 10mM in DMSO |
| PSA | 75.700 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H341: 怀疑引起遗传缺陷
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P281: 根据需要使用个人防护设备。 P271: 仅在室外或通风良好的地方使用。
WGK Germany：
3
Personal protective equipment：
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS：
XF8060000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
298-93-1 | Thiazolyl Blue Tetrazolium Bromide.pdf
